Hbio Thursday and Friday April 30th and May 1st

Journal
Notes...
quiz next class on

•DNA structre
•DNA replication vocabulary words…posted on blog!

DNA Replication Vocabulary see below

Helicase unwinding breaks H bonds (green)

Single Strand Binding Protein stabilizer

DNA Polymerase III adds DNA to primer (orange)

Primase RNA primer (pink)

DNA Polymerase I replaces primer (yellow)

DNA Ligase Glues 5’ and 3’ ends (turquoise)

Topoisomerase corrects over-winding

Origin of Replication where synthesis starts

Leading Strand works towards the replication fork

Lagging Strand works away from the replication fork

Okazaki Fragments lagging strand fragments

Telomers base buffers

Telomerase enzymes that add telomers in germ cells to cancer cells

Parent Strand The strand of DNA that serves as a template to make the “phantom” strand (dark black)

Daughter Strand The strand we are trying to make by using the original DNA template (light blue)

Mismatch pair: incorrect base pairing

Proofreading: done by DNA Polymerase III which removes or adds bases as needed

Nuclease: cuts out the mismatch pair

Nucleotide excision repair: uses ligase and DNA polymerase to fix a mismatch
Polymerase fills gaps
Ligase fuses gaps