cancer reading questions

Print out and bring to class

Cancer Reading Questions

Please answer the following questions on a separate piece of paper. These questions are fair game for the test.
Please DO NOT WRITE on the cancer reading, it is just a reading to get done in class.
Feel free to talk this information over with your peers!

Questions:
How are bacterial infections and cancer infections different?
Damage Control: Tumor Suppressor Genes
What four things do normal cells have in place as a way of damage control?
What is cellular suicide called?
How is necrotic cell death different from apoptosis?
P53 is a key protein involved in detecting cellular damage, what are three of its major functions?
What happens when the gene coding for p53 is mutated?
What is the definition of a tumor suppressor gene? What are some of the jobs these genes encode proteins to do?
Why is a mutation in a tumor suppressor gene bad?
Promoting Cellular Division: oncogenes
What happens when protoncogenes become oncogenes? Give a few examples
What would happen to a cell that had an oncogene mutation and a tumor suppressor mutation?



11 What are the six hallmarks of cancer cells? Please briefly explain each!

a.
b.
c.
d.
e.
f



Evolution of Tumors:
What are some of the many changes that have to occur in the cell for it to become cancerous?
How is cancer linked to evolution?